Digestan Drug

Digestan is a drug that helps the digestive process digestive enzymes containing or mixtures that are useful for improving digestive function. Digestan beneficial in deficiencies of one or more substances that function in the gastrointestinal tract to digest food. Process of digestion is affected by HCL (stomach acid), digestive enzymes and bile.
The outline digestan useful dosage is as follows:

   1. Pancreatic enzymes

      Pancreatic enzymes in the stocks known as pankreatin and pankrelipase. Both these substances contain amylase, trypsin (protease) and lipase. Pankrelipase derived from animal pancreas, activity was relatively higher than lipasenya pankreatin.

      Pankrelipase deficiency are indicated on the circumstances such as in pancreatic secretions and mukovisidosis pancreatitis. This Ennzim damaged stomach acid so it must be made in tablet form enteral.

      Pancreatic enzyme causes very little side effects. High doses can cause nausea and diarrhea and also hiperurisemia.
   2. Pepsin

      Pepsin is a proteolytic enzyme that is less important compared with pancreatic enzymes. In pepsin deficiency, symptoms are not serious. Total pepsin deficiency found in patients aklorhidria. Failure to secrete gastric acid and pepsin with an adequate stimulus is called gastric akilia, often occurs in patients with pernicious anemia and gastric carcinoma.
   3. Bile

      Bile contains bile acids and konjugatnya. Substances that are essential for human bile are cholic acid sodium salt and acid kenodeoksikolat. Important addition to the absorption of fat, bile is also important for the absorption of fat soluble substances such as vitamins A, D, E and K.

      In large amounts of bile salts can neutralize stomach acid into the duodenum.

      In normal circumstances the liver to secrete bile salt ± 24 g or 700-1000 ml of bile / day.

      Approximately 85% of bile is absorbed at the bottom of the small intestine (enterohepatik circulation), so only 80 mg of bile salts which must be synthesized per day.

      Bile acids increase bile secretion and called choleretic substances, bile salts showed less choleretic activity. Dehidrokolat a cholic acid active semisynthetic primarily to stimulate bile with BM (molecular weight) is low because it is called zaat hidrokoleretik. This substance is only stimulate spending and not prosuksi gall bladder.

      In contrast to cholic acid, acid kenodeoksikolat lowering cholesterol levels in bile. This is useful for overcoming drug cholesterol gallbladder stones in a particular patient.

      Kenodeoksikolat Acid works by reducing cholesterol absorption from the intestine and decreases cholesterol synthesis. When the acid content reaches 70% bile kenodeoksikolat total, then the solution was saturated bile cholesterol becomes saturated.

      Graam bile reduce gastrointestinal mucosal resistance against gastric acid. This fact is thought to have implications for the occurrence of gastritis, peptic tkak and oesophageal reflux.
Source: Pharmacology and therapeutic Indonesia edition IV.
For the selection of drug classes was the right digestion is better and you should consult a doctor.